Red blood cell distribution width (RDW) is a significant predictor of survival in laryngeal cancer patients: systematic literature review and meta-analysis

Background: This systematic literature review and meta-analysis investigated whether the red blood cell distribution (RDW) may predict survival outcomes in laryngeal cancer patients undergoing curative treatment.
 Methods: We conducted an electronic search Medline Scopus using keywords “red width” OR “RDW” AND “laryngeal cancer” “larynx carcinoma” carcinoma,” without time or language restrictions (up to February 2022), for identifying studies investigating prognostic value of RDW with any form a primary endpoint that was set as rate and/or disease-free between 1 10 years after treatment. The research according PRISMA (Preferred Reporting Items Systematic Reviews Meta-Analyses) 2020 reporting checklist.
 Results: digital enabled us identify five studies, were finally included our pooled analysis (survival covered window 2.7-8.3 years). In four enhanced surgical radiation treatment associated poorer (range odds ratio [ORs], 2.28-10.44). analysis, increased conferred over 3-fold higher risk dying during follow-up (OR, 3.37; 95%CI, 1.41-8.10).
 Conclusion: retains clinically important Clinicians could acknowledge this information more aggressive therapy setting narrower values.